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Liver Core By VITACORE

SKU: 19655
RRP from: $49.95

$49.95 $39.96 inc. GST

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  • Supports Healthy Liver Function*
  • Kidney Support*
  • May Help Reduce Liver Toxins*
  • Helps Fight Free Radicals*
  • Promotes Proper Blood Glucose Levels*
  • Powerful Antioxidants*
  • 60 Servings Per Container
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Product Description

The liver is the “bouncer” of the body – it sees what comes in and determines if it gets in and where it goes. The bouncer role is an essential one, since you want to make sure that your nutrition and supplement regimen is getting properly absorbed and transported to the target tissues. Therefore, a healthy liver is paramount. Liver Core  provides everything necessary for proper liver function: detoxification, antioxidant support, and glucose maintenance. Liver and kidney function go hand-in-hand, and the body cannot properly detoxify if those nasty critters aren’t flushed from the body completely. That is why a kidney support matrix with the best botanicals was included in Liver Core to ensure that free radicals, carcinogens, and other toxins are trapped and shipped out!

  • 350 mg of Milk Thistle – As the go-to botanical for liver health, it is proven to enhance liver cell repair and reduce liver toxins
  • 50 mg of Glutathione –As the predominant endogenous antioxidant in the body, this helps fight free radicals using the body’s internal antioxidant systems
  • 100 mg of Acai Berry – a superfruit containing ellagic acid which blocks carcinogens in the kidney and anthocyanins, which are a powerful antioxidant
  • 50 mg of Alpha-Lipoic Acid – a mitochondrial fatty acid that helps the liver with its main job: maintaining proper blood glucose levels
  • 350 mg of Kidney Support Matrix – powerful botanicals like dandelion root to help the kidneys flush out the toxins that are removed from the liver and other tissues

A healthy liver is an important, but often forgotten, piece of the puzzle of proper nutrition. Liver Core is hitting on all cylinders by providing direct liver benefits plus antioxidant and kidney support. One of the keys to this formula is the acai berry – a superfood that truly earns the name, by providing a huge antioxidant boost and carcinogen blockers. Get the most out of your nutrition by keeping your body’s bouncers – the liver and kidney – healthy and functioning optimally with Liver Core!

Ingredient Profile :

Milk Thistle Extract:

Milk thistle is an herb that may be a liver therapeutic compound.

• Milk thistle may increase the rate of protein synthesis in liver cells and encourage subsequent repair after injury to the cells.
• It may also decrease LDL, triglycerides, and heart burn.
• Limited evidence exists, but milk thistle may also have anti-obesity effects.

N-Acetyl Cysteine:

N-Acetyl-Cysteine is an acetylated form of L-Cysteine that is more bioavailable. It is often used for its high antioxidant content to reduce inflammation and counter oxidative stress.

• It also works to bind various free radicals and poisons in the body so they can be removed through the digestive process and expelled.

L-Glutathione:

Glutathione is a substance produced naturally by the liver. It is also found in fruits, vegetables, and meats.

• Glutathione is involved in many processes in the body, including tissue building and repair, making chemicals and proteins needed in the body, and for the immune system.
• Because glutathione is heavily involved in the detoxification of our body, it is no surprise that it is found in its highest concentrations in the liver; the body’s most important detoxifying organ.
• Glutathione is also closely linked to liver health and function, when GSH levels are high, the workload put on the liver is reduced and it has a chance to repair itself.
• This helps reduce liver inflammation which is the cause of liver cirrhosis and impaired liver function.

Dandelion Root:

Taraxacum officinale, also known as dandelion, is a vegetable that has a diuretic (water loss) effect when ingested.

• It is also a source of potassium and thereby helps replace diuresis-induced losses.
• Dandelion may help ease digestion by increasing the rate at which food leaves the stomach and enters the small intestine.
• A study conducted by Clare et al. (2009) found dandelion three times a day in otherwise healthy subjects reported an increase in urination frequency relative to the same subjects the day before and after supplementation.

Uva-Ursi:

Uva-Ursi is an herbal compound which has the effects of a mild diuretic and astringent (anti-inflammatory).

• It helps to reduce accumulation of uric acid in the bladder and help the overall health and productivity of the urinary tract.
• Uva-Ursi may also help reduce high blood pressure and bloating.
• It’s anti-inflammatory effects can help to tighten upper layers of the mucous membrane – relieving irritation and improving tissue firmness.

Alpha Lipoic Acid:

Alpha-Lipoic Acid (ALA) is a mitochondrial fatty acid that is highly involved in energy metabolism. It is synthesized in the body and can be consumed through eating meats and minimally in some fruits/vegetables.

• In supplement form, ALA has shown benefit against various forms of oxidation and inflammation. These effects carry on to benefits that protect one from heart diseases, liver diseases, diabetes, and neurological decline with age.
• ALA is also a potent anti-oxidant compound. It works with mitochondria and the body’s natural anti-oxidant defenses.
• It is also seen as an anti-aging compound since it can reverse some of the oxidant damage related effects of aging.

L-Glycine:

Glycine is a non-essential amino acid that is used to help generate muscle tissue, assist with proper cell growth and production, and convert glycogen into energy. It also plays an important role in proper nervous system function.

• Glycine is required for the biosynthesis of creatine. Glycine increases the body’s creatine levels and helps prevent the breakdown of muscle.
• In the absence of glycine, damaged muscle tissue cannot be repaired.
• Current research has suggested that glycine supplementation may increase growth hormone (GH) levels 3-4 hours post exercise via its stimulatory agents acting upon the pituitary gland. This increase in GH theoretically could lead to faster recovery times and greater muscle growth.

Juniper Berry:

Juniper extract helps fight inflammation and various GI issues including upset stomach, heartburn, flatulence, bloating, and loss of appetite.

• Juniper extract has been used as a diuretic. This activity is most likely due to the action of terpinen-4-ol, which is known to increase renal glomerular filtration rate.

Buchu Powder:

Buchu is harvested from the dried leaves obtained from three species of Barosma.

• Historically, buchu has been used to treat inflammation, kidney and urinary tract infections; and as a diuretic.

Q: What is the best way to take Liver Core?
A: Take One Serving (2 Capsules) daily with a meal.

Q: What physiological functions does the liver serve in the body?
A: The liver plays over 500 roles in the human body but the most important roles are the liver cleans your blood, produces a digestive liquid called bile, and stores energy in the form of glycogen.

Q: What other VitaCore products do you recommend stacking with Liver Core?
A: To promote overall health we recommend stacking Liver Core with Joint Core, Detox Core, Fruits & Greens, Omega Core, and Core Multi-Vita.

References:

Milk Thistle Extract:
1. Mulrow, C., Lawrence, V., Jacobs, B., Dennehy, C., Sapp, J., Ramirez, G., … & Chiquette, E. (2000). Milk thistle: effects on liver disease and cirrhosis and clinical adverse effects: summary.
2. Abenavoli, L., Capasso, R., Milic, N., & Capasso, F. (2010). Milk thistle in liver diseases: past, present, future. Phytotherapy Research, 24(10), 1423-1432.
3. Pradhan, S. C., & Girish, C. (2006). Hepatoprotective herbal drug, silymarin from experimental pharmacology to clinical medicine. Indian Journal of Medical Research, 124(5), 491.

N-Acetyl Cysteine:
1. Holdiness, M. R. (1991). Clinical pharmacokinetics of N-acetylcysteine. Clinical pharmacokinetics, 20(2), 123-134.
2. Wang, L., Wang, Z., & Liu, J. (2010). Protective effect of N-acetylcysteine on experimental chronic lead nephrotoxicity in immature female rats. Human & experimental toxicology, 29(7), 581-591.
3. Kasperczyk, S., Dobrakowski, M., Kasperczyk, A., Ostałowska, A., & Birkner, E. (2013). The administration of N-acetylcysteine reduces oxidative stress and regulates glutathione metabolism in the blood cells of workers exposed to lead. Clinical Toxicology, 51(6), 480-486.
4. Kasperczyk, A., Słowińska-Łożyńska, L., Dobrakowski, M., Zalejska-Fiolka, J., & Kasperczyk, S. (2014). The effect of lead-induced oxidative stress on blood viscosity and rheological properties of erythrocytes in lead exposed humans. Clinical hemorheology and microcirculation, 56(3), 187-195.

L-Glutathione:
1. Amano J, Suzuki A, Sunamori M. Salutary effect of reduced glutathione on renal function in coronary artery bypass operation. J Am Coll Surg 1994;179:714-20. View abstract.
2. Amores-Sanchez MI, Medina MA. Glutamine, as a precursor of glutathione, and oxidative stress. Mol Genet Metab 1999;67:100-5. View abstract.
3. Anderson ME. Glutathione: an overview of biosynthesis and modulation. Chem Biol Interact 1998;24;111-112:1-14.
4. Antioxidant lozenge could help ward off flu. www.reutershealth.com (Accessed 19 April 2000).
5. Aw TY, Wierzbicka G, Jones DP. Oral glutathione increases tissue glutathione in vivo. Chem Biol Interact 1991;80:89-97. View abstract.
6. Bains JS, Shaw CA. Neurodegenerative disorders in humans: the role of glutathione in oxidative stress-mediated neuronal death. Brain Res Brain Res Rev 1997;25:335-58. View abstract.
7. Borok Z, Buhl R, Grimes GJ, et al. Effect of glutathione aerosol on oxidant-antioxidant imbalance in idiopathic pulmonary fibrosis. Lancet 1991;338:215-6. View abstract.

Dandelion Root:
1. Lee et al. 2012; Effects of Taraxacum officinale on fatigue and immunological parameters in mice.
2. Jeon et al. 2008; Anti-inflammatory activity of Taraxacum officinale.
3. Choi et al. 2010; Hypolipidemic and antioxidant effects of dandelion (Taraxacum officinale) root and leaf on cholesterol-fed rabbits.
4. Turski et al. 2011; Distribution, synthesis, and absorption of kynurenic acid in plants.
5. Domitrovic et al. 2010; Antifibrotic activity of Taraxacum officinale root in carbon tetrachloride-induced liver damage in mice.
6. Chaterjee et al 2011; The efficacy of dandelion root extract in inducing apoptosis in drug-resistant human melanoma cells.
7. Ovadje et al 2012; Efficient induction of extrinsic cell death by dandelion root extract in human chronic myelomonocytic leukemia (CMML) cells.

Uva-Ursi:
1. Beaux D, Fleurentin J, Mortier F. Effect of extracts of Orthosiphon stamineus Benth, Hieracium pilosella L., Sambucus nigra L. and Arctostaphylos uva-ursi (L.) Spreng. in rats. Phytother Res. 1999;13(3):222-5.
2. Chauhan B, Yu C, Krantis A, Scott I, Arnason JT, Marles RJ, Foster BC. In vitro activity of uva-ursi against cytochrome P450 isoenzymes and P-glycoprotein. Can J Physiol Pharmacol. 2007;85(11):1099-107.
3. Grases F, Melero G, Costa-Bauza A, Prieto R, March JG Urolithiasis and phytotherapy. Int Urol Nephrol. 1994;26(5):507-11.
4. Head KA. Natural approaches to prevention and treatment of infections of the lower urinary tract. Altern Med Rev. 2008;13(3):227-44.
5. Larsson B, Jonasson A, Fianu S. Prophylactic effect of UVA-E in women with recurrent cystitis: a preliminary report. Curr Ther Res. 1993;53:441-3.
6. Matsuda H, Nakamura S, Tanaka T, Kubo M. [Pharmacological studies on leaf of arctostaphylos uva-ursi (L.) Spreng. V. Effects of water extract from arctostaphylos uva-ursi (L.) Spreng. (Bearberry leaf) on the antiallergic anti-inflammatory activities of dexamethasone ointment.] Yakugaku Zasshi – J Pharm Soc Jpn. 1992;112(9):673-7.
7. Matsuda H, Nakata H, Tanaka T, Kubo M. [Pharmacological study on Arctostaphylos uva-ursi (L.) Spreng. II. Combined effects of arbutin and prednisolone or dexamethazone on immuno-inflammation] Yakugaku Zasshi. 1990;110(1):68-76.

Alpha Lipoic Acid:
1. McNeilly, A. M., Davison, G. W., Murphy, M. H., Nadeem, N., Trinick, T., Duly, E., … & McEneny, J. (2011). Effect of α-lipoic acid and exercise training on cardiovascular disease risk in obesity with impaired glucose tolerance. Lipids in health and disease, 10(1), 1.
2. Zembron-Lacny, A., Slowinska-Lisowska, M., Szygula, Z., Witkowski, K., Stefaniak, T., & Dziubek, W. (2009). Assessment of the antioxidant effectiveness of alpha-lipoic acid in healthy men exposed to muscle-damaging exercise. J Physiol Pharmacol, 60(2), 139-43.
3. Sola, S., Mir, M. Q., Cheema, F. A., Khan-Merchant, N., Menon, R. G., Parthasarathy, S., & Khan, B. V. (2005). Irbesartan and lipoic acid improve endothelial function and reduce markers of inflammation in the metabolic syndrome results of the irbesartan and lipoic acid in endothelial dysfunction (island) study. Circulation, 111(3), 343-348.
4. Ranieri, M., Sciuscio, M., Cortese, A. M., Santamato, A., Di Teo, L., Ianieri, G., … & Megna, M. (2009). The Use and Alpha-Lipoic Acid (ALA), Gamma Linolenic Acid (GLA) and Rehabilitation in the Treatment of Back Pain: Effect on Health-Related Quality of Life. International journal of immunopathology and pharmacology, 22(3 suppl), 45-50.

L-Glycine:
1. Wax, B., Hilton, L., Vickers, B., Gilliland, K., & Conrad, M. (2013). Effects of glycine-arginine-alpha-ketoisocaproic acid supplementation in college-age trained females during multi-bouts of resistance exercise. J Diet Suppl, 10(1), 6-16.
2. Nelson, M. J., Harris, M. B., Boluyt, M. O., Hwang, H. S., & Starnes, J. W. (2011). Effect of N-2-mercaptopropionyl glycine on exercise-induced cardiac adaptations. [Research Support, Non-U.S. Gov’t]. Am J Physiol Regul Integr Comp Physiol, 300(4), R993-R1000..
3. Jacobs, P. L., & Goldstein, E. R. (2010). Long-term glycine propionyl-l-carnitine supplemention and paradoxical effects on repeated anaerobic sprint performance. J Int Soc Sports Nutr, 7, 35. doi: 10.1186/1550-2783-7-35
4. Bloomer, R. J., Tschume, L. C., & Smith, W. A. (2009). Glycine propionyl-L-carnitine modulates lipid peroxidation and nitric oxide in human subjects. [Randomized Controlled Trial Research Support, Non-U.S. Gov’t]. Int J Vitam Nutr Res, 79(3), 131-141.
5. Jacobs, P. L., Goldstein, E. R., Blackburn, W., Orem, I., & Hughes, J. J. (2009). Glycine propionyl-L-carnitine produces enhanced anaerobic work capacity with reduced lactate accumulation in resistance trained males. J Int Soc Sports Nutr, 6, 9. doi: 10.1186/1550-2783-6-9

Juniper Berry:
1. Bisset, NG. Juniperi fructus. 1994;283-285.
2. Janku, I., Hava, M., and Motl, O. [Diuretic substance from juniper (Juniperus communis L.)]. Experientia 6-15-1957;13(6):255-256.
3. Stanic, G, Samarzija, I, and Blazevic, N. Time-dependent diuretic response in rats treated with juniper berry preparations. Phytother Res 1998;12:494-497.

Buchu Powder:
1. Ernst E. Interactions between synthetic and herbal medicinal products Part 1: a systematic review of the indirect evidence. Perfusion 2000;13:4-15.
2. Lis-Balchin, M., Hart, S., and Simpson, E. Buchu (Agathosma betulina and A. crenulata, Rutaceae) essential oils: their pharmacological action on guinea-pig ileum and antimicrobial activity on microorganisms. J Pharm.Pharmacol. 2001;53(4):579-582
3. Fetrow CW, Avila JR. Professional’s Handbook of Complementary & Alternative Medicines. 1st ed. Springhouse, PA: Springhouse Corp., 1999.

Nutritional Info

Additional Information

Size

120 Capsules