MULTICORE ADVANCED MUTI VITAMIN AND HEALTH FORMULA BY VITACORE

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Description

Core Multi-Vita™ is an advanced, therapeutically dosed vitamin, mineral, antioxidant and enzyme formula designed specifically to meet the nutritional demands of athletes in training and fill micronutrient gaps left by an inadequate diet.  Core Multi-Vita goes far beyond the minimum Recommended Daily Intake (RDI), to support optimal nutritional balance and peak physical and mental performance for hardcore athletes and fitness enthusiasts alike. Vitamins and minerals play critical roles in hundreds of bodily functions. Core Multi-Vita acts as a foundation for those nutritional needs and ensures that all the vital micro-nutrients and co-factors are available at the crucial times your body needs to perform optimally.

Ingredient Profile : 

VITAMIN AND MINERAL COMPLEX:\

Vitamin A – Improves resistance to infection and assist in the growth and repair of body tissues, including muscle.

Vitamin C – Offers multiple antioxidant benefits, boosts immune health, and enhances collagen formation. Vitamin C has also been shown to increase fat loss and nitric oxide production.

Vitamin D – Promotes calcium absorption in the gut and maintains adequate serum calcium and phosphate concentrations to enable normal mineralization of bone and to prevent hypocalcemic tetany. Vitamin D has other roles in the body, including modulation of cell growth, neuromuscular and immune function, and reduction of inflammation

Vitamin E – May decrease levels of creatine kinase and malondialdehyde, markers of mechanical and oxidative muscle damage. Hence vitamin E is critical for muscle recovery.

Vitamin K – Best known for its role in helping blood clot, or coagulate, properly. Vitamin K also plays an important role in bone health.

Thiamin – Involved in many body functions, including nervous system and muscle function, the flow of electrolytes in and out of nerve and muscle cells, digestion, and carbohydrate metabolism.

Riboflavin – In addition to producing energy for the body, riboflavin works as an antioxidant, fighting damaging particles in the body known as free radicals.

Niacin – Helps the body make various sex and stress-related hormones in the adrenal glands and other parts of the body. Niacin helps improve circulation, and it has been shown to suppress inflammation.

Vitamin B-6 – Helps the body make several neurotransmitters, chemicals that carry signals from one nerve cell to another. It is needed for normal brain development and function, and helps the body make the hormones serotonin and norepinephrine, which influence mood, and melatonin, which helps regulate the body clock.

Vitamin B12 – Maintains healthy nerve cells, and helps in the production of DNA and RNA, the body’s genetic material. Vitamin B12 works closely with folate to help make red blood cells and to help iron work better in the body.
Biotin – Metabolizes carbohydrates, fats and amino acids, the building blocks of protein.

Pantothenic Acid – Assists in the production of red blood cells, as well as sex and stress-related hormones produced in the adrenal glands. Pantothenic acid is also important in maintaining a healthy digestive tract, and it helps the body use other vitamins, particularly riboflavin.

Folate – Crucial for proper brain function and plays an important role in mental and emotional health.

Boron – Assists in maintaining healthy bones and mental function. Research also suggests boron can increase levels of free testosterone.

Calcium – Critical in the maintenance of bone and protecting the skeleton from degradation. Calcium is also need for muscle contractions to occur.

Phosphorus – Required for every cell in the body to function properly. Also, involved in energy production from ATP and creatine phosphate.

Iodine – Critical for maintaining the health of the thyroid, a gland that secretes hormones that regulate growth and development.

Magnesium – Involved in more than 300 essential metabolic reactions including those involving the metabolism of carbohydrates, fats, and proteins.

Zinc – Involved in cell signaling and therefore, can release hormones and aid in nerve conduction.

Selenium – Works as an antioxidant, especially when combined with vitamin E. Antioxidants like selenium help fight damaging particles in the body known as free radicals. Evidence suggests that selenium may also be critical for muscle strength.

Copper – Necessary for the proper growth, development, and maintenance of bone, connective tissue, brain, heart, and many other body organs. Copper may also increase growth hormone production.

Manganese – Involved in the production of testosterone and the formation of connective tissue.

Chromium – Essential mineral that must be obtained through diet or supplementation. Chromium is involved in glucose metabolism by enhancing the function of insulin.

ENERGY AND FOCUS COMPLEX:

L-Tyrosine:

L-Tyrosine helps to activate metabolic pathways that produce the hormones epinephrine and norepinephrine – which are typically produced during moments of stress on the body and provide a boost in the terms of a “fight or flight” scenario.

• Epinephrine and norepinephrine are depleted quickly during these moments of stress due to a lack of L-Tyrosine.
• The addition of this amino acid to Multi-Vita will help give you an extra PUSH and can make a big difference to help you FIGHT through your workouts and plateaus.
• Hoffman et al. (2010) research results indicate that acute ingestion of supplement including L-tyrosine and anhydrous caffeine, can maintain reaction time, and subjective feelings of focus and alertness to both visual and auditory stimuli in healthy college students following exhaustive exercise.

Choline Complex (CDP Choline/Choline Bitartrate):

Choline is an essential nutrient for brain health and synaptic plasticity.

• Choline improves structural integrity, signaling capacity and the fluidity of neural membranes. It’s estimated that close to 90% of the population does not get the recommended amount of choline daily.
• It has been shown that a dose of 500mg of Choline can boost focus, mood and concentration abilities.
• This is tantamount to pushing through your workout. Utilizing this effectively dosed compound, you will be able to focus on taking less rest or being distracted during you training. Giving your 110% will really be your 110%.
• A study conducted by Sun et al. (1999) reported that subjects who supplemented with choline for 4 weeks improved learning performance and memory compared to a placebo group.

DiCaffeine Malate:

Dicaffeine malate is a stimulant that contains both caffeine and malic acid.

• The malic acid helps calm the digestive effects of caffeine.
• Malic acid is also thought to replenish the energy produced by the caffeine.

ANTIOXIDANT COMPLEX:

MSM:

Low concentrations of MSM in our bodies have been linked with unspecified complaints of fatigue, depression, high sensitivity to physical and psychological stress, and with many degenerative diseases.

Green Tea Extract:
Green Tea is loaded with polyphenols like flavonoids and catechins, which function as powerful antioxidants

Alpha Lipoic Acid:

Many of the benefits of Alpha Lipoic Acid is from its’ anti-oxidant properties and the associated ability to fight free radicals and regenerate other anti-oxidants.

Coenzyme Q10:

Coenzyme Q-10 is produced by the human body and is necessary for the basic functioning of cells.

• CoQ10 can reduce the damage oxidized Low-density Lipoprotein (LDL) can do to blood vessels, as well as reduce plaque buildup in the arteries.
• CoQ10 may able to reduce exercise induced muscle damage. Kon et al. (2008) found individuals supplementing with CoQ10 daily were able to reduce muscular damage associated with exercise and reduce increases in injury related biomarkers (creatine kinase, myoglobin, leukocytes).

Pycnogenol:

Pycnogenol has been shown to be a more effective antioxidant than either vitamin C or vitamin E, because it is so easily absorbed in the bloodstream (absorption takes only 20 minutes) and works for up to 72 hours.

• It also works with vitamin C to help the body recycle vitamin E, and is one the few antioxidants that can cross the blood-brain barrier to help protect brain tissue.
• Because Pycnogenol is such an effective free-radical neutralizer, it is thought to help regenerate systems that generally break down with age, thus improving immune resistance, vision, brain function, and skin elasticity.
• It may also protect cellular DNA from the oxidative damage and cell mutations that can lead to cancer.

Grape Seed Extract:

The polyphenols in grape seeds make them a highly potent antioxidant and protect the body against oxidative and free radical damage.

• Scientific studies show that the antioxidant power of grape seed extract is 20 times more powerful than vitamin E and 50 times greater than vitamin C.
Saw Palmetto Extract:
Contain compounds that may reduce inflammation and strengthen the immune systems.

Lutein:

A carotenoid antioxidant that is most well-known for protecting eye health.

• Lutein also has potent anti-inflammatory benefits.

Piperine:

Piperine can attenuate free radicals and reactive oxygen species and has been shown to protect against oxidative damage.

ADVANCED ENZYME BLEND:

Protease:

Protease helps aid in protein digestion and absorption by breaking it down into amino acids, the building blocks of muscle tissue.

Amylase:

Amylase is an enzyme that is made in the pancreas and salivary glands that aids in the digestion of carbohydrates.

• As a digestive enzyme Amylase acts on the starches found in food, breaking them down into smaller, more digestible carbohydrate molecules which end up as glucose (energy) in the body.

Lipase:

Lipase is a digestive enzyme produced in the liver that breaks down dietary fats into the smaller, more absorbable molecules glycerol and fatty acids.

• In a small clinical study of 18 people, supplements containing lipase and other pancreatic enzymes helped reduce bloating, gas, and fullness following a high-fat meal.

Cellulase:

Cellulase in an enzyme that is responsible for breaking down the plant material and fiber found in food.

• Due to the fibrous cells walls of some plant based food the body is not able to breakdown and utilize the beneficial nutrients found in them.
• Cellulase aids in the breakdown of these cells walls; improving the body’s ability to absorb the nutrients found in them.

Lactase:

Lactase is an enzyme found in the small intestine, liver, and kidney that catalyze the breakdown of lactose (milk sugar) into the simple sugars glucose and galactose.

• Lactase is commonly used to help people who have trouble digesting milk and other dairy products.

Betaine HCL:

Betaine HCL is a source of hydrochloric acid that can be used to increase levels of hydrochloric acid in the stomach.

• This helps activate pepsin, a digestive enzyme that assists with protein digestion by breaking it down into smaller, more easily absorbed amino acids.

Q: What is the best way to take Core Multi-Vita?
A: As a dietary supplement, take 1 serving in the AM with your meal.

Q: Do I need to take a multi-vitamin/mineral?
A: It is highly recommended to supplement with a multi-vitamin/mineral (especially athletes) as research has shown that even the best diets are micronutrient deficient.

Q: What makes Core Multi-Vita better than other multi-vitamins?

A: The level of label transparency and the quality, clinically dosed and effective ingredients that go beyond the RDA recommendations.

Q: What other VitaCore products do you recommend stacking with Multi-Vita?
A: Multi-Vita can be stacked with any other VitaCore product.

References : 

Vitamins and Minerals:
1. Sarris, J., Cox, K. H., Camfield, D. A., Scholey, A., Stough, C., Fogg, E., … & Pipingas, A. (2012). Participant experiences from chronic administration of a multivitamin versus placebo on subjective health and wellbeing: a double-blind qualitative analysis of a randomised controlled trial. Nutrition journal,11(1), 1.
2. Machefer, G., Groussard, C., Vincent, S., Zouhal, H., Faure, H., Cillard, J., … & Gratas-Delamarche, A. (2007). Multivitamin-mineral supplementation prevents lipid peroxidation during “the Marathon des Sables”. Journal of the American College of Nutrition, 26(2), 111-120.
3. Aguiló, A., Tauler, P., Sureda, A., Cases, N., Tur, J., & Pons, A. (2007). Antioxidant diet supplementation enhances aerobic performance in amateur sportsmen. Journal of sports sciences, 25(11), 1203-1210.
4. Misner, B. (2006). Food alone may not provide sufficient micronutrients for preventing deficiency. Journal of the International Society of Sports Nutrition,3(1), 1.

L-Tyrosine:
1. Benedict, C. R., Anderson, G. H., & Sole, M. J. (1983). The influence of oral tyrosine and tryptophan feeding on plasma catecholamines in man. The American journal of clinical nutrition, 38(3), 429-435.
2. Alonso, R., Gibson, C. J., Wurtman, R. J., Agharanya, J. C., & Prieto, L. (1982). Elevation of urinary catecholamines and their metabolites following tyrosine administration in humans. Biological psychiatry, 17(7), 781-790.
3. Agharanya, J. C., Alonso, R., & Wurtman, R. J. (1981). Changes in catecholamine excretion after short-term tyrosine ingestion in normally fed human subjects. The American journal of clinical nutrition, 34(1), 82-87.
4. Acworth, I. N., During, M. J., & Wurtman, R. J. (1988). Tyrosine: effects on catecholamine release. Brain research bulletin, 21(3), 473-477.
5. Neri, D. F., Wiegmann, D., Stanny, R. R., Shappell, S. A., McCardie, A., & McKay, D. L. (1995). The effects of tyrosine on cognitive performance during extended wakefulness. Aviation, space, and environmental medicine.

Choline Complex:
1. Moreno, H., de Brugada, I., & Hall, G. (2013). Chronic dietary choline supplementation modulates attentional change in adult rats. Behavioural brain research, 243, 278-285.
2. Blusztajn, J. K., & Mellott, T. J. (2013). Neuroprotective actions of perinatal choline nutrition. Clinical Chemistry and Laboratory Medicine, 51(3), 591-599.
3. Krzysztof Blusztajn, J., & J Mellott, T. (2012). Choline nutrition programs brain development via DNA and histone methylation. Central Nervous System Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry-Central Nervous System Agents), 12(2), 82-94.
4. Biasi, E. (2011). The effects of dietary choline. Neuroscience bulletin, 27(5), 330-342.

DiCaffeine Malate:
1. Goldstein, E. R., Ziegenfuss, T., Kalman, D., Kreider, R., Campbell, B., Wilborn, C., … & Wildman, R. (2010). International society of sports nutrition position stand: caffeine and performance. J Int Soc Sports Nutr, 7(1), 5.
2. Spriet, L. L. (1995). Caffeine and performance. International journal of sport nutrition, 5, S84-S84.
3. Beck, T. W., Housh, T. J., Schmidt, R. J., Johnson, G. O., Housh, D. J., Coburn, J. W., & Malek, M. H. (2006). The acute effects of a caffeine-containing supplement on strength, muscular endurance, and anaerobic capabilities. The Journal of Strength & Conditioning Research, 20(3), 506-510.
4. McLellan, T. M., Kamimori, G. H., Voss, D. M., Tate, C., & Smith, S. J. (2007). Caffeine effects on physical and cognitive performance during sustained operations. Aviation, space, and environmental medicine, 78(9), 871-877.
5. Lieberman, H. R., Tharion, W. J., Shukitt-Hale, B., Speckman, K. L., & Tulley, R. (2002). Effects of caffeine, sleep loss, and stress on cognitive performance and mood during US Navy SEAL training. Psychopharmacology, 164(3), 250-261.
6. Costill, D. L., Dalsky, G. P., & Fink, W. J. (1977). Effects of caffeine ingestion on metabolism and exercise performance. Medicine and science in sports, 10(3), 155-158.
7. Kovacs, E. M., Stegen, J. H., & Brouns, F. (1998). Effect of caffeinated drinks on substrate metabolism, caffeine excretion, and Performance. Journal of Applied physiology, 85(2), 709-715.

MSM:
1. Debbi, E. M., Agar, G., Fichman, G., Ziv, Y. B., Kardosh, R., Halperin, N., … & Debi, R. (2011). Efficacy of methylsulfonylmethane supplementation on osteoarthritis of the knee: a randomized controlled study. BMC complementary and alternative medicine, 11(1), 1.
2. Kalman, D. S., Feldman, S., Scheinberg, A. R., Krieger, D. R., & Bloomer, R. J. (2012). Influence of methylsulfonylmethane on markers of exercise recovery and performance in healthy men: a pilot study. Journal of the International Society of Sports Nutrition, 9(1), 1-11.
3. Barmaki, S., Bohlooli, S., Khoshkhahesh, F., & Nakhostin-Roohi, B. (2012). Effect of methylsulfonylmethane supplementation on exercise-Induced muscle damage and total antioxidant capacity. The Journal of sports medicine and physical fitness, 52(2), 170-174.
4. Ezaki, J., Hashimoto, M., Hosokawa, Y., & Ishimi, Y. (2013). Assessment of safety and efficacy of methylsulfonylmethane on bone and knee joints in osteoarthritis animal model. Journal of bone and mineral metabolism, 31(1), 16-25.

Green Tea Extract:
1. Effects of ingestion of a commercially available thermogenic dietary supplement on resting energy expenditure, mood state and cardiovascular measures. Outlaw J, Wilborn C, Smith A, Urbina S, Hayward S. J Int Soc Sports Nutr. 2013 Apr 30;10(1):25.
2. Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans. Dulloo AG, Duret C, Rohrer D, Girardier L, Mensi N, Fathi M, Chantre P, Vandermander J. Am J Clin Nutr. 1999 Dec;70(6):1040-5
3. Neurochemical and behavioral effects of green tea (Camellia sinensis): a model study. Mirza B, Ikram H, Bilgrami S, Haleem DJ, Haleem MA. Pak J Pharm Sci. 2013 May;26(3):511-6.
4. The effect of green tea extract on fat oxidation at rest and during exercise: evidence of efficacy and proposed mechanisms. Hodgson AB, Randell RK, Jeukendrup AE. Adv Nutr. 2013 Mar 1;4(2):129-40.
5. Metabolic response to green tea extract during rest and moderate-intensity exercise. Hodgson AB, Randell RK, Boon N, Garczarek U, Mela DJ, Jeukendrup AE, Jacobs DM. J Nutr Biochem. 2013 Jan;24(1):325-34.

Alpha Lipoic Acid:
1. McNeilly, A. M., Davison, G. W., Murphy, M. H., Nadeem, N., Trinick, T., Duly, E., … & McEneny, J. (2011). Effect of α-lipoic acid and exercise training on cardiovascular disease risk in obesity with impaired glucose tolerance. Lipids in health and disease, 10(1), 1.
2. Zembron-Lacny, A., Slowinska-Lisowska, M., Szygula, Z., Witkowski, K., Stefaniak, T., & Dziubek, W. (2009). Assessment of the antioxidant effectiveness of alpha-lipoic acid in healthy men exposed to muscle-damaging exercise. J Physiol Pharmacol, 60(2), 139-43.
3. Sola, S., Mir, M. Q., Cheema, F. A., Khan-Merchant, N., Menon, R. G., Parthasarathy, S., & Khan, B. V. (2005). Irbesartan and lipoic acid improve endothelial function and reduce markers of inflammation in the metabolic syndrome results of the irbesartan and lipoic acid in endothelial dysfunction (island) study. Circulation, 111(3), 343-348.
4. Ranieri, M., Sciuscio, M., Cortese, A. M., Santamato, A., Di Teo, L., Ianieri, G., … & Megna, M. (2009). The Use and Alpha-Lipoic Acid (ALA), Gamma Linolenic Acid (GLA) and Rehabilitation in the Treatment of Back Pain: Effect on Health-Related Quality of Life. International journal of immunopathology and pharmacology, 22(3 suppl), 45-50.

Coenzyme Q10:
1. Lee, B. J., Huang, Y. C., Chen, S. J., & Lin, P. T. (2012). Coenzyme Q10 supplementation reduces oxidative stress and increases antioxidant enzyme activity in patients with coronary artery disease. Nutrition, 28(3), 250-255.
2. Dai, Y. L., Luk, T. H., Yiu, K. H., Wang, M., Yip, P. M., Lee, S. W., … & Siu, C. W. (2011). Reversal of mitochondrial dysfunction by coenzyme Q10 supplement improves endothelial function in patients with ischaemic left ventricular systolic dysfunction: a randomized controlled trial.Atherosclerosis, 216(2), 395-401.
3. Smith-Ryan, A., & Antonio, J. (Eds.). (2013). Sports Nutrition & Performance Enhancing Supplements. Linus Learning.

Pycnogenol:
1. Liu, X., Wei, J., Tan, F., Zhou, S., Würthwein, G., & Rohdewald, P. (2004). Pycnogenol®, French maritime pine bark extract, improves endothelial function of hypertensive patients. Life sciences, 74(7), 855-862.

Grape Seed Extract:
1. Jayaprakasha, G. K., Singh, R. P., & Sakariah, K. K. (2001). Antioxidant activity of grape seed (Vitis vinifera) extracts on peroxidation models in vitro.Food chemistry, 73(3), 285-290.
2. Jayaprakasha, G. K., Selvi, T., & Sakariah, K. K. (2003). Antibacterial and antioxidant activities of grape (Vitis vinifera) seed extracts. Food research international, 36(2), 117-122.

Saw Palmetto Extract:
1. Bertaccini, A., Giampaoli, M., Cividini, R., Gattoni, G. L., Sanseverino, R., Realfonso, T., … & Galasso, R. (2012). Observational database serenoa repens (DOSSER): overview, analysis and results. A multicentric SIUrO (Italian Society of Oncological Urology) project. Archivio italiano di urologia, andrologia: organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica/Associazione ricerche in urologia, 84(3), 117-122.
2. Suter, A., Saller, R., Riedi, E., & Heinrich, M. (2013). Improving BPH symptoms and sexual dysfunctions with a saw palmetto preparation? Results from a pilot trial. Phytotherapy Research, 27(2), 218-226.
3. Gerber, G. S., Kuznetsov, D., Johnson, B. C., & Burstein, J. D. (2001). Randomized, double-blind, placebo-controlled trial of saw palmetto in men with lower urinary tract symptoms. Urology, 58(6), 960-963.

Lutein:
1. Richer, S. P., Stiles, W., Statkute, L., Pei, K. Y., Frankowski, J., Nyland, J., … & Rudy, D. (2002). The lutein antioxidant supplementation trial.Investigative Ophthalmology & Visual Science, 43(13), 2542-2542.
2. Roberts, R. L., Green, J., & Lewis, B. (2009). Lutein and zeaxanthin in eye and skin health. Clinics in dermatology, 27(2), 195-201.

Piperine:
1. Brewer, M. S. (2011). Natural antioxidants: sources, compounds, mechanisms of action, and potential applications. Comprehensive Reviews in Food Science and Food Safety, 10(4), 221-247.

Betaine HCL:
1. Yago, M. R., Frymoyer, A. R., Smelick, G. S., Frassetto, L. A., Budha, N. R., Dresser, M. J., … & Benet, L. Z. (2013). Gastric reacidification with betaine HCl in healthy volunteers with rabeprazole-induced hypochlorhydria. Molecular pharmaceutics, 10(11), 4032-4037.

Amylase:
1. Tormo, M. A., Gil-Exojo, I., de Tejada, A. R., & Campillo, J. E. (2004). Hypoglycaemic and anorexigenic activities of an α-amylase inhibitor from white kidney beans (Phaseolus vulgaris) in Wistar rats. British journal of nutrition, 92(05), 785-790.
2. Carai, M. A., Fantini, N., Loi, B., Colombo, G., Riva, A., & Morazzoni, P. (2009). Potential efficacy of preparations derived from Phaseolus vulgaris in the control of appetite, energy intake, and carbohydrate metabolism.Diabetes, metabolic syndrome and obesity: targets and therapy, 2, 145.

Protease:
1. Mótyán, J. A., Tóth, F., & Tőzsér, J. (2013). Research applications of proteolytic enzymes in molecular biology. Biomolecules, 3(4), 923-942.

Lipase:
1. Heck, A. M., Yanovski, J. A., & Calis, K. A. (2000). Orlistat, a new lipase inhibitor for the management of obesity. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 20(3), 270-279.

Cellulase:
1. Bughrara, S. S., & Sleper, D. A. (1986). Digestion of several temperate forage species by a prepared cellulase solution. Agronomy Journal, 78(1), 94-98.

Lactase:
1. Witte, J., Lloyd, M., Lorenzsonn, V., Korsmo, H., & Olsen, W. (1990). The biosynthetic basis of adult lactase deficiency. Journal of Clinical Investigation, 86(4), 1338.

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